Research & Publicaions
Vidya herbs continuously strives hard on Innovative natural products
Vidya herbs continuously strives hard on Innovative natural products
Chlorogenic Acid Composition and Method for Its use in the treatment of Alzheimer's Disease
Patent No. US10,588,885
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Key words: COVID-19, GRP78, Mpro, Withaferin A
Patent No. US10,588,885
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Ramanaiah I, Sudeep HV, David D, Shyamprasad K. Sub-acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying. BMC Complem Altern M 2019; 19: 159. http://doi.org/10.1186/s12906-019-2576-7.
Naveen P, Lingaraju HB, Deepak M, Medhini B, Shyam Prasad K. Method development and validation for the determination of caffeine, an alkaloid from Coffee arabica by HPLC method. Phcog Res 2018; 10: 88-91.
Naveen P, Lingaraju HB, Priya KS, Shyam Prasad K. Method development and validation for the determination of costunolide from Cinnamomum tamala by HPLC method. Phcog Res 2018; 10: 422-425.
Gouthamchandra K, Sudeep HV, Venkatesh BJ, Shyamprasad K. Chlorogenic acid complex (CGA7), standardized extract from green coffee beans exerts anticancer effects against cultured human colon cancer HCT-116 cells. Food Science and Human Wellness 2017; 6(3): 147-153. https://doi.org/10.1016/j.fshw.2017.06.001
Bramara BVB, Vasavi HS, Sudeep HV, Shyamprasad K. Hydroalcoholic extract from Lepidium meyenii (Black maca) root exerts wound healing activity in Streptozotocin-induced diabetic rats. Wound Medicine 2017; 19: 75-81. https://doi.org/10.1016/j.wndm.2017.10.003
Vasavi HS, Sudeep HV, Lingaraju HB, Shyamprasad K. Bioavailability-enhanced ResveramaxTM modulates quorum sensing and inhibits biofilm formation in Pseudomonas aeruginosa PAO1. Microb Pathog 2017; 104: 64-71. doi: 10.1016/j.micpath.2017.01.015.
Sudeep HV, Gouthamchandra K, Venkatesh BJ, Shyamprasad K. Viwithan, a standardized Withania somnifera root extract induces apoptosis in murine melanoma cells. Phcog Mag 2017; 13: S801-6. doi: 10.4103/pm.pm_121_17
Naveen P, Lingaraju HB, Deepak M, Medhini B, Shyam Prasad K. Method Development and Validation for the Determination of Caffeine, an alkaloid from Coffee arabica by HPLC method. Phcog Res 2017.
Sudeep HV, Venkatakrishna K, Dipak Patel, Shyamprasad K. Biomechanism of chlorogenic acid complex mediated plasma free fatty acid metabolism in rat liver. BMC Complem Altern M 2016; 16: 274. doi: 10.1186/s12906-016-1258-y.
Bioavailability-enhanced ResveramaxTM modulates quorum sensing and inhibits biofilm formation in Pseudomonas aeruginosa
The polyphenols in Pomegranate play important role in exhibiting anti-ageing effects
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Computational studies on the anti-obesity effect of polyphenols from Pomegranate leaf.
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Effect of chlorogenic acid content in roasted coffee on in vitro antioxidant efficiency
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Evaluation of antioxidant activity of medicinal plant extracts produced for commercial purpose
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Antimicrobial efficacy of some natural cosmeceuticals, neutraceuticals and medicinal plant extracts and ultrastructural alterations in food borne pathogens
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Reethi B, Sudeep HV, Lingaraju HB, Shyamprasad K. Effect of Coleus forskohlii extract on the induction of hepatic cytochrome P450 isoenzyme CYP 1A in rats. World Journal of Pharmacy and Pharmaceutical Sciences 2015; 4(1): 1185-1192.
Naveen P, Lingaraju HB, Shyamprasad K. Rapid development and validation of improved reversed-phase high-performance liquid chromatography method for the quantification of mangiferin, a polyphenol xanthone glycoside in Mangifera indica. Phcog Res 2017; 9(2): 215-219. doi: 10.4103/0974-8490.204652
Naveen P, Lingaraju HB, Anitha, Shyamprasad K. Simultaneous determination of rutin, isoquercetin, and quercetin flavonoids in Nelumbo nucifera by high-performance liquid chromatography method. Int J Pharma Investig 2017; 7: 94-100.
Sudeep HV, Gouthamchandra K, Venkatesh BJ, Shyamprasad K. Viwithan, a standardized Withania somnifera root extract induces apoptosis in murine melanoma cells. Phcog Mag 2017; 13: S801-6. doi: 10.4103/pm.pm_121_17
Vasavi HS, Sudeep HV, Lingaraju HB, Shyamprasad K. Bioavailability-enhanced ResveramaxTM modulates quorum sensing and inhibits biofilm formation in Pseudomonas aeruginosa PAO1. Microb Pathog 2017; 104: 64-71. doi: 10.1016/j.micpath.2017.01.015.
Bramara BVB, Vasavi HS, Sudeep HV, Shyamprasad K. Hydroalcoholic extract from Lepidium meyenii (Black maca) root exerts wound healing activity in Streptozotocin-induced diabetic rats. Wound Medicine 2017; 19: 75-81. https://doi.org/10.1016/j.wndm.2017.10.003
Gouthamchandra K, Sudeep HV, Venkatesh BJ, Shyamprasad K. Chlorogenic acid complex (CGA7), standardized extract from green coffee beans exerts anticancer effects against cultured human colon cancer HCT-116 cells. Food Science and Human Wellness 2017; 6(3): 147-153. https://doi.org/10.1016/j.fshw.2017.06.001
Naveen P, Lingaraju HB, Priya KS, Shyam Prasad K. Method development and validation for the determination of costunolide from Cinnamomum tamala by HPLC method. Phcog Res 2018; 10: 422-425.
Ramanaiah I, Sudeep HV, David D, Shyamprasad K. Sub-acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying. BMC Complem Altern M 2019; 19: 159. http://doi.org/10.1186/s12906-019-2576-7.
Gouthamchandra K, Sudeep HV, Amritharaj, Lingaraju HB, Shyamprasad K. SUNCA standardized extract from Helianthus annus L exerts enhanced digestive enzyme activity and subsides obesity through inhibition of C/EBP-α and PPAR-γ expression both in vitro and in vivo model. Pharmacogn. Mag 2019; 15: S538-44.
Sudeep HV, Venkatakrishna K, Amrutharaj B, Anitha, Shyamprasad K. A phytosterol-enriched saw palmetto supercritical CO2 extract ameliorates testosterone-induced benign prostatic hyperplasia by regulating the inflammatory and apoptotic proteins in a rat model. BMC Complem Altern M 2019; 19: 270. http://doi.org/10.1186/s12906-019-2697-z.
Naveen P, Lingaraju HB, Chandrappa S, Anitha S, Shyamprasad K. Development and validation of veratric acid in Tabebuia avellanedae using liquid chromatography-electrospray ionization-mass spectrometry/mass spectrometry-multiple reaction monitoring-based assay coupled with 1,1-diphenyl-2-picrylhydrazyl method. Phcog Res 2020; 12: 107-11. Doi: 10.4103/pr.pr_77_19
Sudeep HV, Gouthamchandra K, Shyamprasad K. Molecular docking analysis of Withaferin A from Withania somnifera with the glucose regulated protein 78 (GRP78) receptor and the SARS-CoV2 main protease. Bioinformation 2020; 16(5): 411-417. Doi: 10.6026/97320630016411.
Sudeep HV, Jestin V Thomas, Shyamprasad K. A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency. BMC Urol 2020; 20: 86. http://doi.org/10.1186/s12894-020-00648-9
Sudeep HV, Amritha Raj, Gouthamchandra K, Chandrappa S, Shyamprasad K. Kinetics and computational analysis of cholinesterase inhibition by REVERC3, a bisdemethoxycurcumin-rich Curcuma longa extract: Relevance to the treatment of Alzheimer’s disease. SAGE Open Med 2020; 8: 1-9.
Sudeep HV, Naveen P, Shyamprasad K. Potential benefits of oral administration of Amorphophallus konjac glycosylceramides on skin health – a randomized clinical study. BMC Complem Med Ther 2020; 20: 26. http://doi.org/10.1186/s12906-019-2721-3
Sudeep HV, Venkatakrishna K, Sudeep K, Vasavi HS, Amritharaj, Chandrappa S, Shyamprasad K. Turcuron: A standardized bisacurone-rich turmeric rhizome extract for the prevention and treatment of hangover and alcohol-induced liver injury in rats. Phcog Mag 2020; 16: S263-71.
Vasavi HS, Sudeep HV, Ramanaiah I, Shyamprasad K. Viwithan: a standardized Ashwagandha extract ameliorates ovalbumin-induced airway-inflammation and oxidative stress in mouse model. 2021; 14(3): 89-93
Naveen P, Lingaraju HB, Chandrappa S, Deepak M, Rashmi R, Shyamprasad K. Isolation, method development, and validation of diterpenes in coffee oil: identification by multiple reaction monitoring approach with atmospheric pressure chemical ionization mode. Phcog Res 2021; 13: 42-8. Doi: 10.4103/pr.pr_66_20
Gouthamchandra K, Sudeep HV, Amritha Raj, Ramanaiah I, Chandrappa S, Shyamprasad K. Bioactive compound bisacurone in the turmeric extract (turcuron) prevents non-alcoholic fatty liver disease by reduction of lipogenesis. IJPER 2021; 55(1s): s48-s55. doi:10.5530/ijper.55.1s.36
Sudeep HV, Gouthamchandra K, Chandrappa S, Naveen P, Reethi B, Venkatakrishna K, Shyamprasad K. In vitro gastrointestinal digestion of a bisdemethoxycurcumin-rich Curcuma longa extract and its oral bioavailability in rats. Bull Natl Res Cent 2021; 45: 84. https://doi.org/10.1186/s42269-021-00544-8
Gouthamchandra K, Sudeep HV, Chandrappa S, Amrith Raj, Naveen P, Shyamprasad K. Efficacy of a standardized turmeric extract comprised of 70% bisdemethoxy-curcumin (REVERC3) against LPS-induced inflammation in Raw 264.7 cells and carrageenan-induced paw edema. J Inflamm Res. 2021; 14: 859-868.
Venkatakrishna K, Sudeep HV, Shyamprasad K. Acute and sub-chronic toxicity evaluation of a standardized green coffee bean extract (CGA-7TM) in Wistar albino rats. SAGE Open Med 2021; 9: 1-12. Doi: 10.1177/2050312120984885
Sudeep HV, Shyamprasad K. Supplementation of green coffee bean extract in healthy overweight subjects increases lean mass/fat mass ratio: A randomized, double-blind clinical study. SAGE Open Med 2021; 9: 1-10. Doi: 10.1177/20503121211002590
A team of highly experienced individuals constantly monitors the quality control procedures ti eliminate any deviations that can hamper the final output
In the product analysis a high degree of accuracy , standardization and quality evaluation of the extracts is being carried out before the dispatch of the consignment to the customer. Our quality control department is well equipped with analytical instruments like HPLC, GC, UV-VIS Spectrophotometer etc..
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